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Vol. 10 No. 3 (2022): Jurnal Keperawatan Padjadjaran

A rare case of Fahr's syndrome with dissociative amnesia

October 5, 2022


Background: Fahr's syndrome (FS) is a movement and psychiatric disorder characterized by symmetrical and bilateral calcification of the basal ganglia. Dissociative amnesia is a rare psychiatric disorder that occurs after stressful events and is classified as a dissociative disorder. In addition, dissociation is the process by which the mind conceals stressful events from consciousness. Several neuropsychiatric manifestations in FS have been reported. However, due to their rarity, FS and dissociative amnesia can be misdiagnosed. Case: A 43-year-old female presented with Parkinsonian symptoms and an inability to recall important personal information. FS and dissociative amnesia were diagnosed after a thorough medical, psychiatric, and diagnostic investigation. Subsequently, correction of calcium and phosphate levels by α-hydroxy-vitamin-73 D3 and psychotherapy were administered for two-months until there were no neuropsychiatric symptoms reported. Conclusion: This research highlights a rare case of FS with dissociative amnesia which pathophysiology is not completely understood due to limited research.

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  1. Abubakar, S., & Saidu, S. (2012). Idiopathic bilateral strio-pallido-dentate calcinosis (Fahr’s disease): A case report and review of the literature. Annals of African Medicine, 11(4), 234-237.
  2. Asokan, A. G., D’souzA, S., Jeganathan, J., & Pai, S. (2013). Fahr’s Syndrome- An Interesting Case Presentation. Journal of Clinical and Diagnostic Research : JCDR, 7(3), 532.
  3. Calabrò, R., Spadaro, L., Marra, A., & Bramanti, P. (2014). Fahr’s disease presenting with dementia at onset: A case report and literature review. Behavioural Neurology, 2014.
  4. El Hechmi, S., Bouhlel, S., Melki, W., & El Hechmi, Z. (2014). [Psychotic disorder induced by Fahr’s syndrome: a case report]. L’Encephale, 40(3), 271-275.
  5. Engelhardt, E. (2020). Cerebral localization of higher functions: Memory-related anatomic structures. Dementia & Neuropsychologia, 14(1), 75.
  6. Grover, S., Ghormode, D., Maheshwari, U., & Kate, N. (2011). Fahr’s disease and psychiatric syndromes: A case series. Industrial Psychiatry Journal, 20(2), 136-138.
  7. Lauterbach, E. C., Cummings, J. L., Duffy, J., Coffey, C. E., Kaufer, D., Lovell, M., Malloy, P., Reeve, A., Royall, D. R., Rummans, T. A., & Salloway, S. P. (1998). Neuropsychiatric correlates and treatment of lenticulostriatal diseases: A review of the literature and overview of research opportunities in Huntington’s, Wilson’s, and Fahr’s diseases. A report of the ANPA Committee on Research. American Neuropsychiatri. The Journal of Neuropsychiatry and Clinical Neurosciences, 10(3), 249-266.
  8. Lee, Y., Park, S., Kim, Y., Park, K., Kim, I., Park, J., & Park, B. (2018). A Case of Seizure Revealing Fahr’s Syndrome with Primary Hypoparathyroidism. The American Journal of Case Reports, 19, 1430-1433.
  9. Lucchelli, F., & Spinnler, H. (2002). The “Psychogenic†Versus “Organic†Conundrum of Pure Retrograde Amnesia: Is it Still Worth Pursuing? Cortex, 38(4), 665-669.
  10. Naqvi, S., Arshad, S., Hanif, R., & Elfert, K. (2017). Fahr’s Syndrome Misdiagnosed as Schizophrenia: A Case Report. Cureus, 9(3), e1071.
  11. Ooi, H. W., Er, C., Hussain, I., Kuthiah, N., & Meyyur Aravamudan, V. (2019). Bilateral Basal Ganglia Calcification: Fahr’s Disease. Cureus.
  12. Perugula, M. L., & Lippmann, S. (2016). Fahr’s Disease or Fahr’s Syndrome? Innovations in Clinical Neuroscience, 13(7-8), 45. /pmc/articles/PMC5022990/
  13. Roiter, B., Pigato, G., & Perugi, G. (2016). Late-Onset Mania in a Patient with Movement Disorder and Basal Ganglia Calcifications: A Challenge for Diagnosis and Treatment. Case Reports in Psychiatry, 2016, 1-5.
  14. Saleem, S., Aslam, H., Anwar, M., Anwar, S., Saleem, M., Saleem, A., & Rehmani, M. (2013). Fahr’s syndrome: Literature review of current evidence. Orphanet Journal of Rare Diseases, 8(1), 1-9.
  15. Samuels, C., Khanni, J., Barkley, K., Azhar, M., & Espinosa, P. (2018). Case Report: An Incidental Finding of Fahr’s Disease in a Patient with Hypochondria. Cureus, 10(12), e3668.
  16. Savino, E., Soavi, C., Capatti, E., Borrelli, M., Vigna, G. B., Passaro, A., & Zuliani, G. (2016). Bilateral strio-pallido-dentate calcinosis (Fahr’s disease): Report of seven cases and revision of literature. BMC Neurology, 16(1), 1-11.
  17. Staniloiu, A., & Markowitsch, H. J. (2014). Dissociative amnesia. The Lancet. Psychiatry, 1(3), 226-241.